At 3 days write-up-MPTP, we discovered substantial microglial activation and up-regulation of CB2 cannabinoid receptors within the ventral midbrain. Cure with Get or even the CB2 receptor agonist JWH015 (4 mg/kg, intraperitoneal) lessened MPTP-induced microglial activation, While genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. Moreover, Persistent Acquire reversed https://win55.clinic/tin-tuc