Pentobarbital will lower the level or result of imatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified. pentobarbital will lessen the level or effect of buprenorphine subdermal implant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Keep an eye on individuals already on buprenorphine subdermal im... https://charlesu777iar8.answerblogs.com/profile