Below, we present that conolidine, a organic analgesic alkaloid used in conventional Chinese drugs, targets ACKR3, thus providing more proof of a correlation between ACKR3 and agony modulation and opening different therapeutic avenues to the treatment of Continual pain. We demonstrated that, in contrast to classical opioid receptors, ACKR3 https://www.proleviate.com/post/what-are-the-side-effects-of-conolidine